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BECKMAN COULTER

Analytical Ultracentrifuge - OPTIMA AUC

An Analytical ultracentrifugation for macromolecule characterization in solution
The Optima AUC combines the power of a centrifuge to provide particle sedimentation with the functionality of optical modules to detect the sedimentation over time. It provides the data you need even faster, so you can make new discoveries in less time
QUOTATION
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lifescience@analis.be
081 25 50 06
QUOTATION
INFORMATION
lifescience@analis.be 081 25 50 06
DESCRIPTION DOWNLOAD VIDEO TESTIMONIAL SPECIFICATIONS
DESCRIPTION
For macromolecule characterization in solution

 

The new Optima AUC system is the most robust technology for providing data used to determine protein molecular weight in basic protein research and quantification of aggregation levels for academic and biopharma research.

The results of AUC are explicit, reliable, and reproducible. AUC is my method of choice to characterize macromolecules and precisely study protein-protein interactions.

Jia Ma, Ph.D. Director
Bioanalytical Core, Purdue University



The Optima AUC combines the power of a centrifuge to provide particle sedimentation with the functionality of optical modules to detect the sedimentation over time. It provides the data you need even faster, so you can make new discoveries in less time.

Summary of features and benefits:

  • Enables sample recovery
  • Avoids dilution effects
  • Analyzes samples in a matrix-free environment
  • Has minimal buffer constraints
  • Enables detection at low concentrations
  • Requires low sample volume (0.1 mL minimum)
  • Delivers high-throughput analysis – up to 7 samples in a single run
  • Requires no standards – relies upon first principles of thermodynamics

Versatility

  • Analyzes a wide array of particles in native, matrix-free conditions, including:

    • Proteins
    • Nanoparticles
    • Peptides
    • Polymers

    • Micelles
    • Liposomes
    • Extracellular
      vesicles

    • Drug conjugates
    • Viral payload

  • Provides data which can answer more critical questions than any other comparable technique, including:

    • Shape
    • Mass
    • Diameter

    • Stoichiometry
    • Heterogeneity
    • Association

    • Aggregation
    • Purity
    • Formulation

  • Enables precise analysis of complex systems at discrete wavelengths (up to 20) in minimal time.

Time Savings

  • Generates faster results as acquisition time is no longer additive.
  • Provides even more scans with the use of an An-50 Ti 8-hole rotor.

Ease of Use

Optima AUC - Ease of Use

  • Modular design provides absorbance and interference optical systems—with the option to install up to 3 independent, simultaneous detection systems (see photo).
  • User-friendly touchscreen display indicates intuitive progression of experimental design.
  • Remote monitoring capabilities let you set up, monitor and extract data from virtually any location.
  • Compatibility with ProteomeLab XL cells and rotors—and widely used analytical software (e.g., UltraScan, SEDFIT/SEDPHAT, SEDANAL, DCDT+)—helps simplify the upgrade process.

Data Quality

  • Delivers cleaner data by providing higher radial resolution and higher signal-to-noise ratio.
  • Delivers higher precision, reproducibility and accuracy than the ProteomeLab XL.

Optima AUC - Live Data Acquisition

 

DOWNLOAD
VIDEO
TESTIMONIAL
SPECIFICATIONS
BECKMAN COULTER website
BECKMAN COULTER
Solutions and systems for clinical diagnostics (hematology, biochemistry, immunoassays, flow cytometry. Solutions for industry & research, for genetics, proteomics and cellular analysis. Lab automated workstation & liquid handling workstation.
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Prices are quoted in euro (taxes excluded) and apply in the Benelux (recycling fee included). They are subject to change without notice. We reserve the right to adjust pricing errors and to limit quantities.

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