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BECKMAN COULTER

Cell Viability Analyzer - Vi-Cell XR

Automated Cell Viability Analysis determining cell concentration and viability accurately and precisely is a requirement in research and in the production of biopharmaceuticals. The Vi-CELL XR automates this process that eliminates variability inherent in manual sample preparation and counting.
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DESCRIPTION

The Vi-Cell XR takes cell viability assy's to a new level

The measurement of overall health of cell cultures requires accurate measurements of both cell concentration and percentage of viable cells. This data is essential to the decision making process for basic tissue culture cell passage and maintaining optimum culture conditions in bioreactors. Vi-CELL applications include research and the growing areas of recombinant protein production and assays for future innovative disease therapies.

The Beckman Coulter Vi-CELL automates the widely accepted trypan blue cell viability tissue culture protocol. Historically, cell viability determinations have been traditionally performed manually using a light microscope and hemacytometer. This technique has major shortcomings. The hemacytometer itself has a significant accuracy error. Different technicians analyzing the same cell population will obtain a spread of results due to the subjective nature of the determination, in addition the method is tedious and time consuming. However, in comparison with the manual technique, the Vi-CELL process means the number of cells quantified in each analysis is significantly greater.

Consequently, the Vi-CELL enhances the statistical reliability of the results. Results are obtained in minutes, and the number of parameters for the cell culture is significantly more comprehensive than those available using the hemacytometer.


TECHNICAL SPECIFICATIONS

Overall Analysis Range : Size Range: 2 µ - 70 µ

Instrumentation function :

- CONCENTRATION : Conc Range: 5x10e4 to 1x10e7 cells per mL

- CELL VIABILITY : Viability Range: 0   100%

- CELL COUNT : Counting Accuracy: ±6%

Operating System: Windows® 2000 / XP

Analysis Rate: User definable Capacity:

Single position or 12 Samples via autoloader

Dimensions : H=44.5 cm / W=38 cm / D=41 cm

Instrumentation Type:Video imaging flow through cell.

 


The Vi-CELL Cell Viability Analyzer provides an automatic and cost effective means to perform the trypan blue dye exclusion method. This data is essential to the decision making process for basic tissue culture cell passage and maintaining optimum culture conditions in bioreactors. Cell and tissue culture applications in life science research, including recombinant protein and biopharmaceutical production, require the accuracy, precision and automation available only in the Vi-CELL cell viability analyzer.

Determining cell concentration and viability accurately and precisely is a requirement in research and in the production of biopharmaceuticals. The Vi-CELL XR automates this process that eliminates variability inherent in manual sample preparation and counting.

The Vi-CELL allows users to load up to 10 samples at once for easy and automated cell counting.  The automated trypan blue staining procedure can be customized to ensure consistent and accurate cell counts for simple systems such as CHO cells and more complex samples such as yeast.  The robust design provides many years of duty, and can be operated by individuals with a wide variety of skill levels.  The high quality, pre-mixed reagents help eliminate variability.

The cell type function within the Vi-CELL Control Software enables users to optimize the unit for many different cell species, including CHO Cells, yeast cells, white blood cells, and a host of other common cells.  The cell type function takes into account cell clumping, cell circularity, cell brightness, cell diameter, and several other pertinent parameters.  This capability enables rapid, accurate, and reliable automated cell counting.  Further, the cell type function can be customized for unusual cell species that may be of interest in specific industrial or academic settings.   


Features

Automated Cell Viability Analysis

The Vi-CELL Cell Viability Analyzer provides an automatic and cost effective means to perform the trypan blue dye exclusion method. This data is essential to the decision making process for basic tissue culture cell passage and maintaining optimum culture conditions in bioreactors. Cell and tissue culture applications in life science research, including recombinant protein and biopharmaceutical production, require the accuracy, precision and automation available only in the Vi-CELL cell viability analyzer.

The Vi-CELL automates the widely accepted trypan blue cell exclusion method. Historically, cell viability determinations were performed manually using a light microscope and hemacytometer. This technique has major shortcomings due to subjective determination of cell count, as well as manual, time consuming steps. In comparison to the manual technique, the Vi-CELL automatically performs the trypan blue with video imaging of the flow-through cell. Results are obtained in minutes.

Product Features

  • % Viability
  • Total cell concentration
  • Total viable cell concentration
  • Mean cell size
  • Real time cellular images
  • Bioprocess monitoring
  • Validated reagents
  • Convenient reagent pack
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BECKMAN COULTER website
BECKMAN COULTER
Solutions and systems for clinical diagnostics (hematology, biochemistry, immunoassays, flow cytometry. Solutions for industry & research, for genetics, proteomics and cellular analysis. Lab automated workstation & liquid handling workstation.
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Prices are quoted in euro (taxes excluded) and apply in the Benelux (recycling fee included). They are subject to change without notice. We reserve the right to adjust pricing errors and to limit quantities.

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