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Freeze Dryers Double-Chambers for Production - DS-Version

Ice Condenser Capacities from 12 kg to more than 500 kg
Shelf area ranges from 1 m² (specifically for process optimisation) to over 40 m², depending on the system type.
Production systems for aseptic production of active ingredients
081 25 50 50
generaluse@analis.be 081 25 50 50

Freeze-drying systems for your high-quality product manufacturing

We support you all the way from the first laboratory trials through the demanding task of process development to the high-quality production of your valuable products.

Our many years of experience and expertise in the design and manufacture of production systems enables us to provide application-specific solutions fully tailored to the needs of our customers.

We typically manufacture production systems with ice condenser capacities from 20 kg to 500 kg or more. Either single-chamber or double-chamber systems can be used, depending on the characteristics of the product.

We cover the full spectrum of typical applications with three basic system types.

Advantages of the CHRIST double-chamber-system:

  • Ice condenser control and access through the chamber door
  • Simple cleaning of drying and ice ice condenser chamber
  • Minimization of sealings to facilitate service and maintenance works
  • Large cross-section between drying chamber and the ice condenser chamber,
    water vapour dissipation to the ice condenser is optimized
  • Short distances for the water vapour, therefore high efficiency
    and economic operation of the unit
  • Reduced pressure difference between ice condenser and drying chamber,
    therefore sensitive as well as low eutectic substances can be dried
  • Full automatic sterilzation process (SIP) with
    121°C or 134°C including cooling and vacuum test, filter integrity test
  • Clean-In-Place (CIP) available as on option
  • Flexible measurement and control system

A comprehensive range of double-chamber-systems is available, starting
with 12 kg ice condenser capacity up to more than 500 kg and shelf areas from 0.63 m2 to > 40 m2.



Production systems for aseptic production of active ingredients (double-chamber systems)

Custom system projects

Long before your system dries the first batch of your valuable product, our qualified project management, engineering and service team provides the necessary advice and support for everything from system design, seamless quality control during production, on-time installation, commissioning and qualification, and ensuring the reproducible and trouble-free long-term operation of your freeze drying system. If technical problems arise, you can count on fast response from our Service team 24/7, 365 days a year.

Structural or component positioning modifications for adaptation to space constraints are possible, as well as alternative arrangements for vacuum, cooling and control. We offer a broad selection of solutions at various levels for secure freeze dryer loading and unloading solutions, which is naturally a significant issue for users. They range from configurations with attached isolators to semi-automatic loading carts and fully automatic loading and unloading systems. The latter systems can be implemented conventionally using conveyor belts or transfer carts, or innovatively using cleanroom robots for unparalleled precision and reliability. Mature solutions are assured by our ‘best partner’ approach, which means working with leading specialists in their fields. Christ normally assumes the role of lead supplier to minimise the number of contact persons.

All systems and equipment fulfil the most stringent requirements with regard to the materials used and functional safety, and they are extensible and upgradable for future applications. Advanced automation concepts simplify operation for users and ensure fully reproducible drying processes. Our experts are active in major associations and working groups, including ISPE and the German PAT group, and are therefore familiar with stringent regulatory requirements, particularly with regard to the pharmaceutical and biotech industries.

We work with users to devise system and loading concepts for an extremely wide range of tasks and process requirements and implement them in manufacturable designs.

The double-chamber design developed by Christ places the ice condenser directly below the drying chamber. There is a wide choice of sizes, with ice condenser capacities from 12 kg to more than 500 kg. The shelf area ranges from 1 m² (specifically for process optimisation) to over 40 m², depending on the system type.

Our Epsilon DS freeze drying systems feature:

  • Pressure chamber > 2.5 bar for steam sterilisation (SIP)
  • Hydraulic/pneumatic door locking system
  • Stainless steel door (optional slot door)
  • Automatic filter test (FIT)
  • Siemens S7 control system with LPCplus
  • Optional cleaning in place (CIP) capability
  • Compact design with minimum space requirements

Typical applications

  • Pharmaceutical industry (e.g. aseptic production of vaccines, cytostatic agents)
  • Biopharmaceutical industry
Martin Christ is one of the leading manufacturers of freeze drying units world-wide, with an experience of more than 50 years and offers an entire program of laboratory, pilot and production plants for all applications.
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Prices are quoted in euro (taxes excluded) and apply in the Benelux (recycling fee included). They are subject to change without notice. We reserve the right to adjust pricing errors and to limit quantities.