The LSCplus series offers a variety of options to optimise your freeze drying processes. In addition to documentation and key parameter analysis, the automatic determination of critical product data is also available.
Our intelligent systems even offer the option of automatic tuning for set values based on current process conditions. As a result, these laboratory freeze dryers offer numerous options for supporting process development and optimisation, which can provide important findings designed to enable confidence in scale-up conditions.
Our LyoRx sensor monitors electrical resistance as well as the product temperature. The resulting profile data can be utilised by our LyoControl software for the automatic determination of your product freezing point.
The benefit to your process is a reliable estimation of the critical product temperature tolerances during the main drying phase to prevent product melting.
The LyoRx sensor enables the automatic control of the energy supply of the individual shelves during the main drying phase, which makes it possible to limit the thawing effects of the product, for example. The integration is realised via the LyoBus module.
In order to measure the product temperature, every shelf can be equipped with a PT-100 sensor. The product temperatures on the various shelves can be viewed in the LSCplus control system. The integration is realised via the LyoBus module.
Pressure increase test
The transition from the main drying phase to the secondary drying phase can be initiated with our automatic pressure increase test. Christ solutions include an integrated valve bet- ween the product chamber and the ice condenser. This valve is briefly oscillated during the main drying phase. If the pressure increase within the product chamber remains below set limits whilst the valve is closed our system can determine, no further sublimation water left in the product and the secondary drying phase can be initiated.
Comparative pressure measurement
The use of two different vacuum sensors (Pirani and capacitive principle of measurement) enables conclusions to be made concerning the end of the main drying phase. When the diffe- rence of the pressure measurement falls below a predefined limit, the secondary drying phase will be started automatically.