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BECKMAN COULTER

Therapeutic Drug Monitoring : QMS Tacrolimus (TAC)

Now available on the BECKMAN COULTER AU480/680/5800 series : A new comprehensive menu of immunosuppressive drug monitoring kits  : QMS® Tacrolimus, QMS® Everolimus, CEDIA® Cyclosporine Plus and CEDIA® Mycophenolic Acid
QUOTATION
INFORMATION
bioclinical@analis.be
081 25 50 50
QUOTATION
INFORMATION
bioclinical@analis.be 081 25 50 50
DESCRIPTION DOWNLOAD
DESCRIPTION
Therapeutic Drug Monitoring :
QMS Tacrolimus Assay(TAC)
for the BECKMAN COULTER  AU480/AU680/AU5800 Clinical Chemistry Systems

The Thermo ScientificTM QMS® Tacrolimus assay is intended for the quantitative determination of tacrolimus in human whole blood on automated clinical chemistry analyzers. The results obtained are used as an aid in the management of kidney, liver, and heart transplant patients receiving tacrolimus therapy.
This in vitro diagnostic device is intended for clinical laboratory use only.
The QMS Tacrolimus Immunoassay is a homogeneous particle-enhanced turbidimetric immunoassay. The assay is based on competition between drug in the sample and drug coated onto a microparticle for antibody binding sites of the tacrolimus antibody reagent. The tacrolimus-coated microparticle reagent is rapidly agglutinated in the presence of the anti-tacrolimus antibody reagent and in the absence of any competing drug in the sample. The rate of absorbance change is measured photometrically at 700 nm. When a sample containing tacrolimus is added, the agglutination reaction is partially inhibited, slowing down the rate of absorbance change. A concentration-dependent classic agglutination inhibition curve can be obtained with the maximum rate of agglutination at the lowest tacrolimus concentration and the lowest agglutination rate at the highest tacrolimus concentration.


Features of the Tacrolimu s Assay

› Ready-to-Use liquid reagent
› Low-End sensitivity (LOQ = 1.0 ng/mL)
› Correlation to LC-MS/MS
› Reportable range (1-30 ng/mL)
› Reproducibility across assay range

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BECKMAN COULTER website
BECKMAN COULTER
Solutions and systems for clinical diagnostics (hematology, biochemistry, immunoassays, flow cytometry. Solutions for industry & research, for genetics, proteomics and cellular analysis. Lab automated workstation & liquid handling workstation.
Prices are quoted in euro (taxes excluded) and apply in the Benelux (recycling fee included). They are subject to change without notice. We reserve the right to adjust pricing errors and to limit quantities.

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